Eric Dane Reveals ALS Battle: “This Isn’t the End of My Story”

June 13, 2025: Grey’s Anatomy and Euphoria star Eric Dane has opened up publicly for the first time about his battle with amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease. The 52-year-old actor appeared visibly emotional in a new Good Morning America interview with Diane Sawyer, calling the diagnosis a daily reality he cannot ignore.

“I wake up every day and I’m immediately reminded that this is happening,” Dane told Sawyer. “It’s not a dream.”

In a heartfelt 30-second teaser for the upcoming segment, Dane is seen tearfully holding Sawyer’s hand and reflecting on his journey. Despite the seriousness of his condition, he remains hopeful:

“I don’t think this is the end of my story. I don’t feel like this is my end.”

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A Beloved Career and Family Life

Dane rose to fame playing Dr. Mark Sloan — aka “McSteamy” — on Grey’s Anatomy from 2006 to 2012, with a return cameo in 2021. He later starred in hit films like Marley & Me (2008), Valentine’s Day (2010), and Burlesque (2010), before leading the TNT drama The Last Ship and most recently portraying the controversial Cal Jacobs in HBO’s Euphoria.

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Dane first revealed his ALS diagnosis in April this year. In a statement at the time, he expressed gratitude for his family’s support:

“I have been diagnosed with ALS. I am grateful to have my loving family by my side as we navigate this next chapter.”

He shares two daughters — Billie Beatrice, 15, and Georgia Geraldine, 13 — with actress Rebecca Gayheart.

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What Is ALS?

Often referred to as Lou Gehrig’s disease, ALS is a rare and incurable condition that progressively attacks the nerve cells responsible for controlling muscles. Early symptoms include muscle twitching, limb weakness, or slurred speech, eventually progressing to full-body paralysis.

According to the Mayo Clinic and the Muscular Dystrophy Association, patients typically survive three to five years post-diagnosis — though some live far longer. Notable long-term survivors include physicist Stephen Hawking, who lived with ALS for over 50 years.

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Looking Ahead

Eric Dane’s courage in going public with his diagnosis has already touched many fans around the world. His emotional interview with Diane Sawyer is expected to shed more light on his personal struggle and inspire greater awareness around ALS.

“I kindly ask that you give my family and I privacy during this time,” Dane said earlier.

His full interview is scheduled to air soon on Good Morning America.